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Low and Mighty: How Low-Affinity Antibodies Boost Cancer Immunotherapy

Our body is constantly guarded by our immune system, which defends us from external threats like viruses and bacteria, and even internal rogue cells that can become cancerous. Antibodies, which are special proteins in our bodies, play a key role in this defence. They work... click to read more

  • Christian Orr | Beamline Scientist at Diamond Light Source
  • Chelsea Norman | Senior Laboratory Technician at Rosalind Franklin Institute
  • Mark Cragg | Professor at University of Southampton
Views 1108
Reading time 4 min
published on Sep 8, 2023
Engineered probiotic boosts cancer therapy

Cancer immunotherapy has revolutionized cancer treatment in the past decade. In principle, cancer immunotherapy works by improving a patient's immune system to recognize and eliminate cancer cells. Our immune system detects and attacks foreign cells or substances, such as bacteria or viruses. Despite coming from... click to read more

Views 1615
Reading time 3.5 min
published on Apr 19, 2023
How do immune cells enter tissues to protect the body?

Most cells in our body don’t move: they stay put, forming dense tissues. But one population of cells moves continually, and we would not survive without them. These immune cells arrive at any spot in our body where damage or infection arises. Immune cells... click to read more

Views 2181
Reading time 3.5 min
published on Jan 17, 2023
Can nerve signals put a halt to type 1 diabetes?

In type 1 diabetes the immune system goes awry, but the reasons why are not completely understood, and we lack treatments to control type 1 diabetes. We found that nerve signals may hold one key to solving the mystery. Normally your blood sugar level is... click to read more

  • Gustaf Christoffersson | Assistant Professor at Department of Medical Cell Biology, Science for Life Laboratory, Uppsala University, Sweden
Views 2888
Reading time 3 min
published on Feb 16, 2022
Our blood may be making us smarter

There is nothing subtle about the immune system. T cells, potent immune cells found in the blood, can kill just about anything. In response to a viral infection, T cells move in, kill any of your cells that have a virus inside them, coordinate a... click to read more

Views 4251
Reading time 4 min
published on Mar 1, 2021