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We publish short lay-summaries ("breaks") of scientific research. Our authors are scientists involved in the field of the summarized research. Our readers are academics and laypeople likewise. Learn more.
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Feisty fish and birds with attitude: Why does evolution not lead to identical individuals?
Natural selection is often thought to “perfect” an organism. Yet, real organisms show lots of diversity in their behaviours and morphology. We show that competition for resources can either maintain trait diversity at a constant high level, or lead to wild cycles in trait evolution. Continuous differences in resources like those found in nature are an important part of these outcomes.
Tobacco smoking and other exposures shut off cancer-fighting genes
Aug 31, 2024 | 3 min read by Jüri Reimand , Nina AdlerStacking molecular chips in multiple dimensions
Aug 30, 2024 | 3 min read by Lucía Gallego , Romain Jamagne , Michel RickhausA hidden clock that times cytoplasmic divisions
Aug 30, 2024 | 3 min read by Cindy OwAmmonia Energy: A Call for Environmental Awareness
Aug 29, 2024 | 3.5 min read by Matteo Bertagni , Robert Socolow , Amilcare PorporatoWhen two kinases go for a dance
Aug 2, 2024 | 4 min read by Ioannis Galdadas , Francesco Luigi Gervasio , Pauline JuyouxHighlights
Making nature compute for us
Jan 27, 2023 in Maths, Physics & Chemistry | 4 min read by Martin M. SteinPlant genetic engineering makes treasure from trash
Feb 27, 2023 in Plant Biology | 3.5 min read by Dennis Kleinschmidt , Joachim FornerOrb-weaving spiders can hear using their web
Feb 10, 2023 in Evolution & Behaviour | 4 min read by Jian Zhou , Junpeng Lai , Ronald Hoy , Ronald MilesSubjects
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When two kinases go for a dance
Phosphorylation is a fundamental mechanism in eukaryotic cells that allows signals to propagate. Kinases orchestrate this process by phosphorylating proteins to modulate their activity. Our work reveals the architecture of the complex between two key players of the mitogen-activated protein kinase signaling pathway, p38α and MKK6, while also giving an idea of what happens when the two come together.
Aug 2, 2024 | 4 min readFeisty fish and birds with attitude: Why does evolution not lead to identical individuals?
Natural selection is often thought to “perfect” an organism. Yet, real organisms show lots of diversity in their behaviours and morphology. We show that competition for resources can either maintain trait diversity at a constant high level, or lead to wild cycles in trait evolution. Continuous differences in resources like those found in nature are an important part of these outcomes.
Aug 31, 2024 | 3 min readAwakening the thymus to cure SARS-CoV-2 infection: a matter of genes
Establishing an appropriate immune response is essential to recover from viral diseases such as COVID-19.The thymus, an organ of the immune system, plays a vital role in producing new T-lymphocytes that help eliminate the virus that causes COVID-19. We recently discovered that a genetic trait determines the effectiveness of thymic activity in fighting this virus, and thus the clinical outcome.
Jul 27, 2024 | 3.5 min readStacking molecular chips in multiple dimensions
Our quest is to control how molecules come together to form large assemblies. In our earlier studies we showed that we can stack saddle-shaped molecular chips into neat columns that then stick together laterally to form 2D sheets, but can we limit this process to form different morphologies? Here we show how blocking the sides of the columns equalizes the secondary interaction, yielding 1D fibers.
Aug 30, 2024 | 3 min readTobacco smoking and other exposures shut off cancer-fighting genes
DNA mutations causing cancer occur in cells through aging, environmental exposures, and cellular factors. By analysing thousands of cancer genomes, we found that tobacco smoking, APOBEC enzymes, and oxidative stress often introduce harmful “stop-gain” mutations that disable genes. This study highlights how some lifestyle choices and cellular processes can modify genes that protect us from cancer.
Aug 31, 2024 | 3 min readA hidden clock that times cytoplasmic divisions
Our recent study reveals that in fruit fly embryos, the cell's cytoplasm can divide on its own, without waiting for the nucleus or relying on the usual cell division signals. This discovery challenges what we thought we knew about how cells divide and opens up new questions about how these processes are controlled.
Aug 30, 2024 | 3 min read