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cancer

number of breaks: 10

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Tumor infiltrating immune cells predict patient outcomes

There has been much investigation into the role of the body's immune system in fighting or promoting the development of cancer, and in recent years, one particular type of immune cell, the CD8 T cell, has been shown to be important for fighting cancer in... click to read more

  • Caroline S. Jansen | MD/PhD Student at Department of Urology, School of Medicine; Winship Cancer Institute; Department of Microbiology and Immunology, School of Medicine; Emory Vaccine Centre, School of Medicine; Emory University , Atlanta, GA, USA
  • Haydn T. Kissick | Assistant Professor at Department of Urology, School of Medicine; Winship Cancer Institute; Department of Microbiology and Immunology, School of Medicine; Emory Vaccine Centre, School of Medicine; Emory University , Atlanta, GA, USA
Views 443
Reading time 3 min
published on Oct 14, 2020
The Janus-Faced Nature of Cancer Immunity

Cancer, viruses, bacteria, and chemicals are threatening our bodies every day. The weapon our body uses to fight these threats is our immune system. When triggered by the presence of something it perceives as foreign (and therefore danger), our immune system will produce antibodies targeting... click to read more

  • Chih-Wei Lin | Staff Scientist at The Scripps research institute, San Diego, California, USA
  • Richard Lerner | Professor at The Scripps research institute, San Diego, California, USA
Views 658
Reading time 3.5 min
published on Sep 21, 2020
Vicious Circles – how changes in the shape of DNA can drive cancer

The diploid human genome contains 23 pairs of chromosomes whose DNA encodes genes for life activities, such as cell division. Cancer corrupts those genes, making growth-promoting genes more active (oncogenes) or growth-inhibiting genes (tumor suppressors) less active. One of the most common genetic alterations causing... click to read more

  • Sihan Wu | Postdoctoral Research Fellow at Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA, USA
  • Paul S. Mischel | Professor at Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA, USA
Views 820
Reading time 3.5 min
published on Aug 17, 2020
Ten cigarettes in a bottle of wine for cancer

Do you drink one small glass of wine a day? Four pints of beer a week? Did you know drinking at even these relatively low levels can increase your risk of cancer? Less than 15% of the population are aware of a link between alcohol... click to read more

  • Theresa Hydes | Postdoctoral Research Fellow at University Hospital Southampton NHS Foundation Trust, Southampton, Hampshire, UK
Views 2078
Reading time 3.5 min
published on Aug 9, 2019
Shuttle service for metastatic cancer cells

The majority of cancer-related deaths are due to the spread of cancer cells throughout the body, a process called metastasis. While we still do not fully understand how metastasis works, an important role is attributed to the "disobedience" of a patient's own immune cells. In... click to read more

  • Barbara M. Szczerba | PhD student at University of Basel, Basel, Switzerland
  • Nicola Aceto | Assistant Professor at University of Basel, Basel, Switzerland
Views 1432
Reading time 3 min
published on Aug 7, 2019