The human genome contains around 20,000 genes with two copies per gene, one inherited from each parent. Changes in the genome including gene breaks, rearrangements, and extra gene copies are frequent in many diseases, most commonly in cancer. DNA breaks occur often throughout the genome,... click to read more

Expression of a correct set of genes at the right time is crucial for cells to maintain their cell-type specific function. Epigenetic cell memory supports maintenance of such gene expression programs, with specific chromatin states regulating which genes to express or to keep silent. Chromatin... click to read more

If you traveled back in time to approximately two billion years ago, you would see an Earth completely devoid of animals and plants. Yet, at microscopic levels, life is on the brink of one of the greatest and unique developments in history. Two single celled... click to read more