Nature has always been an interesting source of chemical diversity for the search of molecules of therapeutic interest. Here we showed how large plant extract libraries can be transformed into a chemical library. This library could then be efficiently used to isolate molecules of unreported bioactivity to advance our knowledge on disease treatments.

Epigenetic regulation consists in chemical modifications on the proteins that organize DNA. Here, we show how it increases gene copies and rearranges the MLL gene, which associates with infant, adult, and therapy-associated leukemia. These findings show how chemotherapy-induced MLL changes occur and provide a therapeutic way to prevent them.

A fixed point is a point that does not move when subjected to a given transformation. Theorems guaranteeing the existence of such points have a wide application not only in mathematics, but also in economics or in Google's search engine. Such a new theorem has recently been discovered: every isometry has a fixed point when viewed in an extended space.

Ultrasound is key for detecting breast cancer. However, current bulky, planar imaging devices do not fit the unique breast shape well. We have developed a new conformable Ultrasound Breast Patch (cUSBr-Patch), which overcomes this with a flexible transducer array, nature-inspired honeycomb patch, and accurate signal processing. This breakthrough allows breast ultrasound to become wearable, operator-independent, and more accessible.

Upon biting, blood sucking insects inject an anti-coagulant to enjoy their meal. These anti-coagulants have inspired approved drug. Combining this concept with supramolecular chemistry, we developed a novel bi-functional drug. It shows strong in vivo effects and can be reversed with an 'antidote,' a sought-after trait in anti-coagulant treatments. This property extends to other therapies like immunotherapies, broadening its potential impact on diverse medical applications.

The rich energy structure of ultracold molecules (at -459 °F or -273 °C),  gives rise to collisional dynamics where the state-of-the-art models are inadequate for describing collisional resonances. We have discovered a pronounced magnetically tuned resonance in collisions between two NaLi molecules, which enhances the chemical reaction rate by more than a factor of a hundred.