schizophrenia

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Two hits in one – the neurobiology of schizophrenia

Schizophrenia is a severe psychiatric disorder, affecting about one percent of the population worldwide. Perturbation of pre-natal development is known to contribute to the disease, although onset typically occurs between late adolescence and early adulthood. This led to formulation of the ‘two-hit’ hypothesis: the disruption... click to read more

Andrew Pocklington | Senior Lecturer at Cardiff University

schizophrenia

psychiatric genetics

pathobiology

neurodevelopment

stem cell differentiation

Reading time 3 min

published on Jan 31, 2023

Genes that influence handedness alter brain architecture

For at least 10,000 years, approximately 90% of humans have preferred using the right hand over the left. The question of why about one in ten people are left-handed has fascinated scientists for centuries, but no clear answer has yet emerged. We already knew that genetic... click to read more

Akira Wiberg | Postdoctoral Research Fellow at University of Oxford, Oxford, UK

Gwenaëlle Douaud | Associate Professor at University of Oxford, Oxford, UK

Dominic Furniss | Associate Professor at University of Oxford, Oxford, UK

genetics

brain

language

handedness

schizophrenia

Reading time 3 min

published on Aug 10, 2020