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partner with:

immunotherapy

number of breaks: 3

showing 1-3 of 3 breaks

Taking cardiac fibrosis down with engineered immune cells

Heart disease, in its many forms, is one of the most prominent causes of death and suffering, especially in developed countries. One of the hallmarks of most heart diseases is fibrosis, characterized by excessive deposition of the extracellular matrix. Limited amounts of this matrix normally... click to read more

  • Joel G. Rurik | PhD student at Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
  • Jonathan A. Epstein | Professor at Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
Views 685
Reading time 4 min
published on Jun 3, 2020
Shuttle service for metastatic cancer cells

The majority of cancer-related deaths are due to the spread of cancer cells throughout the body, a process called metastasis. While we still do not fully understand how metastasis works, an important role is attributed to the "disobedience" of a patient's own immune cells. In... click to read more

  • Barbara M. Szczerba | PhD student at University of Basel, Basel, Switzerland
  • Nicola Aceto | Assistant Professor at University of Basel, Basel, Switzerland
Views 1309
Reading time 3 min
published on Aug 7, 2019
Empowering the immune system to fight against cancer

It is well known that to grow and invade different organs, tumours must find ways to evade several layers of controls that are in place in our body. The immune system, a complex network of cells and antibodies has been shaped by evolution to protect... click to read more

  • Giovanni Germano | Postdoctoral Research Fellow at School of Medicine, University of Torino, Turin, Italy
Views 2376
Reading time 3.5 min
published on Oct 22, 2018