While humans are 99.999% the same at the DNA level, there are small variations in our DNAs known as alleles. Most differences in our alleles are harmless, but some alleles make us more susceptible to get diseases like cancer or dementia. Understanding how these alleles... click to read more

The brain regulates changes in its own blood flow depending on how active its cells (neurons) are, by a mechanism called neurovascular coupling. When neurons become active, they send messages to nearby blood vessels causing them to dilate and bring in more blood. This increased... click to read more

Alzheimer's disease (or "AD"), the leading cause of dementia, is a progressive brain disorder that causes problems with memory and thinking. More than five million patients in the United States are currently diagnosed with AD. The goal of our research is to help each person... click to read more