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drug discovery

number of breaks: 3

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New chemistry in unusual bacteria displays drug-like activity

 Where do drugs come from? Most clinical molecules are either produced by chemists in a laboratory, or naturally in living organisms. While synthetic chemistry is a pipeline to drug discovery, nature-made molecules continue to have an important role as drug templates. Certain soil bacteria called... click to read more

  • Grace Dekoker | Undergraduate Research Assistant at Washington University in St. Louis
  • Joshua Blodgett | Professor at Washington University in St. Louis
Views 2186
Reading time 3.5 min
published on Mar 21, 2023
New treatment options for Zika virus infection

The recent outbreak of the Zika virus in South America in 2015-2016 had devasting consequences, involving at least 200,000 human infections. The Zika virus mostly spreads among people through bites from infected mosquitoes, but can also spread through sexual transmission. The number of infections are... click to read more

  • Rachel P. M. Abrams | Postdoctoral Research Fellow at National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
  • Avindra Nath | Senior Investigator at National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
Views 3116
Reading time 3.5 min
published on Jun 2, 2021
Fighting food pathogens with the help of a soil bacterium

Enterohemorrhagic Escherichia coli (EHEC) is a notorious foodborne pathogen, typically associated with consumption of undercooked red meat. The infamous "burger bug", most commonly caused by a subspecies called "O157:H7" is responsible for causing a severe form of food poisoning, which can reach beyond the gut... click to read more

  • Rebecca McHugh | PhD student at University of Strathclyde, Glasgow, United Kingdom and University of Glasgow, Glasgow, United Kingdom
Views 4220
Reading time 3 min
published on Aug 16, 2019