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Health & Physiology

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Gene therapy and ALS: one step closer to the clinic

Amyotrophic lateral sclerosis (ALS) is a devastating disease that on average kills in only 3 to 5 years after diagnosis, and for which there is still no cure today. ALS patients have progressive muscle weakness, leading to gradual paralysis and difficulties breathing which will usually... click to read more

  • Florie Borel | Postdoctoral Research Fellow at Horae Gene Therapy Center, University of Massachusetts Medical School, USA
  • Christian Mueller | Associate Professor at Horae Gene Therapy Center; Department of Pediatrics, University of Massachusetts Medical School, USA
Views 440
Reading time 4 min
published on Mar 6, 2019
BioBits™: Making Hands-on Biology Experiences Accessible for Everyone

Molecular biology is difficult to teach in schools, since the concepts can't be seen and are instead represented with abstract diagrams in textbooks. Some schools have introduced hands-on activities, such as growing cells that glow green, to illustrate these ideas in real life and facilitate... click to read more

  • Ally Huang | PhD student at Massachusetts Institute of Technology, Department of Biological Engineering, USA
  • Jessica Stark | PhD student at Department of Chemical and Biological Engineering, Northwestern University, USA
  • Peter Nguyen | Wyss Technology Fellow at Wyss Institute for Biologically Inspired Engineering, Harvard University, USA
Views 336
Reading time 3.5 min
published on Feb 22, 2019
Gene edited “superpigs” resist devastating disease

Genome editors are simple tools that allow scientists to make very precise changes to the genome of any organism by cutting the genome at a very precise location. If you imagine the genome as a single, continuous string of information containing the instructions to build... click to read more

  • Christine Burkard | Assistant professor at The Roslin Institute, University of Edinburgh, Edinburgh, UK
Views 713
Reading time 4.5 min
published on Feb 13, 2019
Keeping CRISPR under control: how bacteria fight viruses without harming themselves

Bacteria are in a constant struggle with the viruses that infect them. While we often think of bacteria as agents of infection, bacteria are in turn infected by viruses, called phage. The phage that infect bacteria and archaea are the most abundant class of organism... click to read more

Views 406
Reading time 4 min
published on Jan 14, 2019
Scutoid cell blocks: a (energetically) cheap way of life

Breaking news! Believe it or not, we are formed by cells! Well, to be honest, we know this since 1665 when Robert Hooke discovered and named the fundamental constituents of all animals. Hooke performed pioneering microscopy and biological studies but, in addition, he was also... click to read more

  • Pedro Gómez-Gálvez | PhD student at Departamento de Biología Celular, Universidad de Sevilla and Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla. Seville, Spain
  • Luis M. Escudero | Principal Investigator at Departamento de Biología Celular, Universidad de Sevilla and Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla. Seville, Spain
  • Javier Buceta | Principal Investigator at Bioengineering Department and Chemical and Biomolecular Engineering Department, Lehigh University. Bethlehem, PA 18018, USA
Views 775
Reading time 4 min
published on Jan 7, 2019