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Health & Physiology

showing 16-20 of 151 breaks

Visualizing the initial steps of blood clotting by SARS-Cov2 Spike protein

SARS-Cov-2 is a respiratory virus responsible for COVID-19 infections that can be severe or even fatal. Peculiar to SARS-Cov-2, compared to other coronaviruses, is its tendency to lead to blood clotting defects, which are involved in the major causes of severe COVID-19 complications (like microthrombosis,... click to read more

Views 1503
Reading time 3.5 min
published on Oct 9, 2023
Writing cell memory: how Histones play a role in Epigenetic Memory

Expression of a correct set of genes at the right time is crucial for cells to maintain their cell-type specific function. Epigenetic cell memory supports maintenance of such gene expression programs, with specific chromatin states regulating which genes to express or to keep silent. Chromatin... click to read more

  • Valentin Flury | Postdoctoral Research Fellow at University of Copenhagen
  • Anja Groth | Professor at University of Copenhagen
Views 1735
Reading time 4 min
published on Oct 4, 2023
How HIV-infected cells use immune checkpoints to evade the human immune system

About 38 million people live with Human Immunodeficiency Virus (HIV) worldwide and hopes for a significant reduction of new transmissions have only partially materialized. In contrast to other infectious diseases that can be readily cured with short-term antimicrobial treatment, HIV-1 infection remains incurable and requires... click to read more

Views 1193
Reading time 4 min
published on Sep 27, 2023
Age-induced unsealing of the "Pandora's box": resurrection of endogenous retroviruses

Human evolution is like a tightrope walker with viruses – in a delicate balance. Endogenous retroviruses (ERVs), once part of ancient retroviral infections, are now permanently fixed in our genome. Most of them, including human ERVs (HERVs), like landmines buried in the past, accumulate mutations... click to read more

Views 1127
Reading time 3.5 min
published on Sep 20, 2023
Low and Mighty: How Low-Affinity Antibodies Boost Cancer Immunotherapy

Our body is constantly guarded by our immune system, which defends us from external threats like viruses and bacteria, and even internal rogue cells that can become cancerous. Antibodies, which are special proteins in our bodies, play a key role in this defence. They work... click to read more

  • Christian Orr | Beamline Scientist at Diamond Light Source
  • Chelsea Norman | Senior Laboratory Technician at Rosalind Franklin Institute
  • Mark Cragg | Professor at University of Southampton
Views 1523
Reading time 4 min
published on Sep 8, 2023