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Health & Physiology

showing 31-35 of 96 breaks

De-liver-ing blood and immune cells to the developing human

Some blood and immune disorders have origins during early human development. To treat these diseases effectively, we must understand what is occurring during normal development and how critical changes in cellular expansion could lead to disease. In adulthood, our blood and immune cells are made in... click to read more

  • Emily Stephenson | PhD student at Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
  • Laura Jardine | Lecturer at Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
Views 2021
Reading time 3 min
published on Aug 25, 2020
Vicious Circles – how changes in the shape of DNA can drive cancer

The diploid human genome contains 23 pairs of chromosomes whose DNA encodes genes for life activities, such as cell division. Cancer corrupts those genes, making growth-promoting genes more active (oncogenes) or growth-inhibiting genes (tumor suppressors) less active. One of the most common genetic alterations causing... click to read more

  • Sihan Wu | Postdoctoral Research Fellow at Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA, USA
  • Paul S. Mischel | Professor at Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA, USA
Views 1784
Reading time 3.5 min
published on Aug 17, 2020
The importance of being tested

Imagine the global threat of a potentially lethal virus, showing up in mainland China and rapidly spreading worldwide, for which no effective treatments or vaccines are available. A few months ago, this would have been nothing more than a book or a movie plot. Unfortunately, it... click to read more

  • Giulia Giordano | Assistant Professor at Department of Industrial Engineering, University of Trento, Trento, Italy
Views 4898
Reading time 3.5 min
published on Jul 15, 2020
Your biological age within a drop of your blood

If we took a blood sample from you and one from your elderly grandmother, could you tell which sample came from which person just by looking at the molecules in the blood? In our recent study published in Nature Medicine, we addressed this question and... click to read more

  • Benoit Lehallier | Instructor at Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA
Views 2126
Reading time 3.5 min
published on Jul 3, 2020
Treating Alzheimer's disease with a known anticoagulant: insights from lab mice

Alzheimer's disease (AD) is the most common form of dementia and has been long described as a disease of neurons. Although this is true (neurons are indeed sick and eventually die during AD), the events leading to this are numerous, and not all of them... click to read more

  • Marta Cortes-Canteli | Miguel Servet Researcher at Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain
Views 1884
Reading time 3.5 min
published on Jun 23, 2020