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Genetic determinants of thinness and obesity: cards of the same deck

Obesity is a major public health concern worldwide, with high prevalence paralleling an increasingly "obesogenic" environment that promotes a sedentary lifestyle and poor-quality food choices. However, even within this environment, some people are able to maintain a healthy body mass index (BMI, defined as weight... click to read more

  • Fernando Riveros-Mckay | Postdoctoral Research Fellow at Wellcome Sanger Institute, Cambridge, United Kingdom
  • Inês Barroso | Director of Research at MRC Epidemiology Unit, University of Cambridge, Cambridge, UK
Views 2131
Reading time 3.5 min
published on Jul 12, 2019
"Peeling back the onion": a multi-layered approach to understand the dynamics of sleep

We now know that a good night's sleep is essential for maintaining optimal brain functioning and health. Many will have experienced the acute detrimental effects of "pulling an all-nighter" on attention and performance, which are usually quickly remedied by sleep. Chronically curtailed or disrupted sleep... click to read more

  • Maxime Jan | Postdoctoral Research Fellow at Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland
  • Paul Franken | Professor at Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland
Views 2826
Reading time 4 min
published on Apr 17, 2019
Gene edited “superpigs” resist devastating disease

Genome editors are simple tools that allow scientists to make very precise changes to the genome of any organism by cutting the genome at a very precise location. If you imagine the genome as a single, continuous string of information containing the instructions to build... click to read more

  • Christine Burkard | Assistant professor at The Roslin Institute, University of Edinburgh, Edinburgh, UK
Views 3187
Reading time 4.5 min
published on Feb 13, 2019
Ancient Egyptian mummies give up the last of their secrets

Our group together with an international team of scientists successfully recovered and analyzed ancient DNA from Egyptian mummies dating from approximately 1400 BC to 400 AD, establishing ancient Egyptian mummies as a reliable source for genetic material to study the ancient past. The study, published... click to read more

  • Johannes Krause | Professor at Max Planck Institute for the Science of Human History, Kahlaische Straße 10 07745, Jena, Germany
Views 6264
Reading time 3.5 min
published on May 15, 2018
Lego blocks for precise gene editing

DNA is the core-element of life as we know it. It can be imagined as a long helical double strand composed of sequences of information written with four chemical "letters" called nucleotides. Determinate sequences of letters delineate stretches of DNA called genes, which in turn... click to read more

  • Jared Carlson-Stevermer | PhD student at Department of Biomedical Engineering, Wisconsin Institute for Discovery, University of Wisconsin-Madison, WI, USA
Views 4656
Reading time 4 min
published on Feb 6, 2018