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showing 36-40 of 47 breaks

Discovery of high-order drug synergies – from impossible to dirt cheap

By combining two or more drugs together (synergistic drug approach) it is possible to obtain a greater effect than with an individual drug alone. For example, the treatment of many diseases, ranging from cancer to tuberculosis to chronic diseases, depends on the use of three... click to read more

  • Murat Cokol | Associate Professor at Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey
Views 3453
Reading time 3.5 min
published on Aug 2, 2018
Killing C. difficile with targeted strikes

Clostridium difficile is a bacterium that causes hundreds of thousands of antibiotic-associated diarrhoea cases every year, and these infections often prove fatal. Usually, C. difficile is unable to cause disease as the bacterium is kept in check by the friendly bacteria in the gut; the... click to read more

  • Joseph Kirk | Postdoctoral Research fellow at The Krebs Institute, MBB, The University of Sheffield, Sheffield S10 2TN, UK
Views 4389
Reading time 3.5 min
published on Jul 24, 2018
The unexpected partner(s): a billion viruses

What constitutes a human body? What is it that makes your body, your own? If we begin to break it down, you can easily see that your body is covered with a layer of hair and skin. Beneath that lie your circulatory systems, bones and... click to read more

  • Jeremy J. Barr | Lecturer at School of Biological Sciences, Monash University, Clayton, Australia
Views 4518
Reading time 4 min
published on Jun 28, 2018
Studies of the bugs within: telling sickness from cure

Each of us carries intestinal gardens, where microbes process food for our own consumption. We evolved to benefit from this, but as our guests are selfish single-cell creatures, tense diplomacy was always needed. Since these bacterial communities in our gut play surprisingly large roles in... click to read more

  • Sofia K. Forslund | Junior Group Leader at Max Delbrück Center for Molecular Medicine & European Molecular Biology Laboratory, Berlin, Germany
  • Oluf Pedersen | Professor at Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark
Views 4179
Reading time 4 min
published on Mar 20, 2018
Gut microbes as a novel anti-aging intervention?

Ours is a world dominated by microbes. Diverse microbial communities colonize just about any available space, even deep within our bodies' cavities. Remarkably, every human being carries as many bacterial as human cells, leading us to question the very meaning of what constitutes a human.... click to read more

  • Miriam Popkes | PhD student at Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Str. 9b D-50931, Cologne, Germany
  • Dario Riccardo Valenzano | Professor at Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Str. 9b D-50931, Cologne, Germany
Views 4322
Reading time 4 min
published on Mar 6, 2018