Life, as we know it, exists thanks to membranes. As active functional barriers between a living cell and its environment, and between compartments within the cell, membranes ensure selective entry and exit of substances, energy generation, and the sending, receiving, and processing of signals essential... click to read more

Bacteria survive in an array of environments, so they are constantly exposed to a wide variety of toxic molecules. To be able to survive in different environments, bacterial cells must be able to actively protect themselves from toxins. Often they do this by breaking down... click to read more

We share an intimate mutual relationship with the microbes in our gut, which we call gut microbiome. It helps us digest and absorb nutrients from our food, and also support our immune system to develop and function properly. Despite considerable progress in our understanding of... click to read more

The discovery of antibiotics made many bacterial infections easily curable. However, today the world is facing a 'post-antibiotic era' crisis as bacteria are rapidly evolving new ways to resist antibiotics. Yearly, 700, 000 deaths are caused by bacterial infections that are untreatable with currently available... click to read more

Microbes in the human gut play essential roles in maintaining human health. Gut microbes carry out many of these roles using a large toolkit of enzymes that can metabolize and transform larger, complex compounds into smaller compounds. Microbial enzymes breakdown many compounds from the human... click to read more