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antimicrobial resistance

number of breaks: 10

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New and Improved! A supercharged antibiotic to fight superbugs

Have you taken an antibiotic lately? You're not alone. Almost one in two people will have been dosed with an antibiotic over the last year. Unfortunately, all this antibiotic use is causing the bacteria to become more and more resistant to the drug's effects. We... click to read more

  • Mark A. T. Blaskovich | Senior Research Officer at Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, Brisbane Qld 4072, Australia
Views 342
Reading time 4.5 min
published on Nov 9, 2018
Bacteria under stress: cheating to survive

As scientists, we often think of bacteria as free-swimming, lone cells, growing in test tubes. Indeed, the majority of experiments are performed in this kind of environment. However, in reality, bacteria often grow in groups of cells, attached to surfaces. These cellular communities are social;... click to read more

  • Isabel Frost | Postdoctoral Research Fellow at The Center For Disease Dynamics, Economics & Policy, Washington, DC, USA
Views 338
Reading time 4 min
published on Oct 15, 2018
Absent microbial teachers and immunological hooliganism

The trillions of microbes that live in our gastrointestinal tract are known as the gut microbiome. It is an "acquired organ" of the body that is essential for the development of immune and metabolic systems and for nutrient digestion and absorption, among other things. As... click to read more

  • Jun Miyoshi | Postdoctoral Research Fellow at Knapp Center for Biomedical Discovery (KCBD), The University of Chicago, Chicago, USA
  • Eugene Chang | Professor at Knapp Center for Biomedical Discovery (KCBD), The University of Chicago, Chicago, USA
Views 348
Reading time 4 min
published on Sep 26, 2018
Discovery of high-order drug synergies – from impossible to dirt cheap

By combining two or more drugs together (synergistic drug approach) it is possible to obtain a greater effect than with an individual drug alone. For example, the treatment of many diseases, ranging from cancer to tuberculosis to chronic diseases, depends on the use of three... click to read more

  • Murat Cokol | Associate Professor at Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey
Views 930
Reading time 3.5 min
published on Aug 2, 2018
Killing C. difficile with targeted strikes

Clostridium difficile is a bacterium that causes hundreds of thousands of antibiotic-associated diarrhoea cases every year, and these infections often prove fatal. Usually, C. difficile is unable to cause disease as the bacterium is kept in check by the friendly bacteria in the gut; the... click to read more

  • Joseph Kirk | Postdoctoral Research fellow at The Krebs Institute, MBB, The University of Sheffield, Sheffield S10 2TN, UK
Views 1140
Reading time 3.5 min
published on Jul 24, 2018