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Microbiology

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Gut bacteria drive yo-yo dieting

The American reality show "The Biggest Loser" features obese contestants that are competing for the strongest weight loss within the duration of one season of the TV series, which is rewarded with a cash prize. A wide audience has followed the show, and its concept... click to read more

  • Eran Elinav | Professor at Weizmann Institute of Science, Rehovot, Israel
Views 412
Reading time 3.5 min
published on Oct 3, 2018
Absent microbial teachers and immunological hooliganism

The trillions of microbes that live in our gastrointestinal tract are known as the gut microbiome. It is an "acquired organ" of the body that is essential for the development of immune and metabolic systems and for nutrient digestion and absorption, among other things. As... click to read more

  • Jun Miyoshi | Postdoctoral Research Fellow at Knapp Center for Biomedical Discovery (KCBD), The University of Chicago, Chicago, USA
  • Eugene Chang | Professor at Knapp Center for Biomedical Discovery (KCBD), The University of Chicago, Chicago, USA
Views 344
Reading time 4 min
published on Sep 26, 2018
Consumed to death: bacteria cause their own extinction by over-polluting the environment

Living means consuming resources, we buy food to get fed, clothes to stay warm and burn oil and coal to have energy. Where things are consumed waste is produced. However, this waste does not simply disappear but mountains of trash form, plastic covers the ocean... click to read more

  • Christoph Ratzke | Postdoctoral Research Fellow at Physics of Living Systems, Department of Physics, Massachusetts Institute of Technology, Cambridge, MA, USA
  • Jonas Denk | PhD student at Arnold-Sommerfeld-Center for Theoretical Physics and Center for NanoScience, Ludwig-Maximilians-Universität München, Munich, Germany
Views 554
Reading time 2.5 min
published on Sep 11, 2018
Discovery of high-order drug synergies – from impossible to dirt cheap

By combining two or more drugs together (synergistic drug approach) it is possible to obtain a greater effect than with an individual drug alone. For example, the treatment of many diseases, ranging from cancer to tuberculosis to chronic diseases, depends on the use of three... click to read more

  • Murat Cokol | Associate Professor at Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey
Views 929
Reading time 3.5 min
published on Aug 2, 2018
Killing C. difficile with targeted strikes

Clostridium difficile is a bacterium that causes hundreds of thousands of antibiotic-associated diarrhoea cases every year, and these infections often prove fatal. Usually, C. difficile is unable to cause disease as the bacterium is kept in check by the friendly bacteria in the gut; the... click to read more

  • Joseph Kirk | Postdoctoral Research fellow at The Krebs Institute, MBB, The University of Sheffield, Sheffield S10 2TN, UK
Views 1139
Reading time 3.5 min
published on Jul 24, 2018